Breadcrumb Home About Tyks Tyks organization Result groups Tyks Department of Paediatrics and Adolescent Medicine Neonatology Baby Friendly Ventilation – research Baby Friendly Ventilation – research The objective of the Baby Friendly Ventilation Study group is to study different respiratory support modes in order to optimize the given support. The study group operates at the NICU of the Turku University Hospital. The main topics of our research are: Control of breathing Work of breathing during different respiratory support modes The effect of different ventilator modes on infant's physiology The effect of different medications on breathing The effect of the implementation of NAVA ventilation on different clinical outcomes. The respiratory centre in the brainstem controls breathing by sending an impulse to the diaphragm via the phrenic nerve to activate the diaphragm. NAVA ventilation is based on the continuous measurement of this electrical activity with a special nasogastric tube (EAdi catheter) including miniature electrodes. The EAdi signal is amplified, digitalized and filtered and transmitted to the ventilator. The signal is then used as a neural trigger for each breath resulting in better synchrony between the patient and the ventilator. In NAVA ventilation, the patient also controls the respiratory frequency, inspiratory time, inspiratory pressure and the termination of breath. The Baby Friendly Ventilation Study Group: Vilhelmiina Parikka Neonatologi, LT Arata Oda Neonatologi, LL Heli Mäntylä Tutkimushoitaja Hanna Soukka Lastentautien erikoislääkäri, LT, dosentti Neonatologi Liisa Lehtonen Head of department Neonatal Intensive Care Unit (NICU) Juyoung Lee Professori Katarzyna Piątek Tutkijalääkäri Show all Publications Soukka H, Lehtonen L. Clinical Protocol: Neonatal ICU, Neurally Adjusted Ventilatory Assist, NAVA. Critical Care News 2013. Soukka H, Grönlund L, Leppäsalo J, Lehtonen L. The effects of skin-to-skin care on the diaphragmatic electrical activity in preterm infants. Early Hum Dev 2014; 90(9): 531-534. Soukka H, Parikka V, Lehtonen L. Kokemuksia NAVA-hoidosta Tyksin vastasyntyneiden teho-osastolla. Finnanest 2015; 48(3): 239-241. Parikka V, Beck J, Zhai Q, Leppäsalo J, Lehtonen L, Soukka H. The Effect of Caffeine Citrate on Neural Breathing Pattern in Preterm Infants. Early Hum Dev 2015; 91: 565-568. Soukka H, Grönlund L, Leppäsalo J, Lehtonen L. The effects of skin-to-skin care on the diaphragmatic electrical activity in preterm infants. Early Hum Dev 2014; 90(9): 531-534. (2.122) Parikka V, Beck J, Zhai Q, Leppäsalo J, Lehtonen L, Soukka H. The Effect of Caffeine Citrate on Neural Breathing Pattern in Preterm Infants. Early Hum Dev 2015; 91: 565-568. (2.122) Oda A, Parikka V, Lehtonen L, Soukka H. Rapid respiratory transition at birth as evaluated by electrical activity of the diaphragm in very preterm infants supported by nasal CPAP. Respiratory Physiology & Neurobiology 2018, 254: 1-4 Oda A, Lehtonen L, Soukka H. Neurally adjusted respiratory support can be used to wean infants with congenital diaphragmatic hernias off respiratory support. Acta Paediatr 2018; 107(4): 718-9. Oda A, Parikka V, Lehtonen L, Porres I, Soukka H. Nasal high flow therapy decreased electrical activity of the diaphragm in preterm infants during the weaning phase. Acta Paediatr 2019 Feb;108(2):253-257. doi: 10.1111/apa.14485. Epub 2018 Jul 25. Soukka H, Parkkola R, Lehtonen L. Brain growth in extremely preterm infants before and after implementing NAVA ventilation. Acta Paediatr 2021; 00: 1-3. Lee J, Parikka V, Lehtonen L, Soukka H. Backup ventilation during neurally adjusted ventilatory assist in preterm infants. Pediatr Pulmonol. 2021 Jul 26. doi: 10.1002/ppul.25583. Online ahead of print. Lee J, Parikka V, Lehtonen L, Soukka H. Parent-infant skin-to-skin contact reduces the electrical activity of the diaphragm and stabilizes respiratory function in preterm infants. Pediatr Res. 2021 Jun 4:1-5. doi: 10.1038/s41390-021-01607-2. Online ahead of print. Oda A, Parikka V, Lehtonen L, Azimi S, Porres I, Soukka H. Neurally adjusted ventilatory assist in ventilated very preterm infants: a crossover study. Pediatr Pulmonol 2021 Aug 26. doi: 10.1002/ppul.25639. Online ahead of print. Piatek K, Lehtonen L, Parikka V, Setänen S, Soukka H. Implementation of neurally adjusted ventilatory assist and high flow nasal cannula in very preterm infants in a tertiary level NICU. Pediatr Pulmonol 2022. Print this page